Skip to content
GERICLINICS

Clinical case · Myelodysplastic neoplasms

Tired, pale and a low platelet count

An 80-year-old woman has macrocytic anaemia and mild thrombocytopenia with no reversible cause. Read her marrow and genetic results and classify her disease under the WHO 2022 scheme.

Advanced 15 minNeeds clinical reviewPro · free in beta

You will learn to

  • Apply the WHO 2022 cytopenia and dysplasia thresholds
  • Classify MDS by blast count and defining genetic abnormalities
  • Tell MDS apart from clonal cytopenia (CCUS) and CMML

Presentation

Step 1 of 10

An 80-year-old woman has felt more tired and breathless on stairs over six months. Her GP found a low haemoglobin and platelet count and referred her.

References

  1. Khoury JD, Solary E, Abla O, et al. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms. Leukemia. 2022;36(7):1703–1719. doi:10.1038/s41375-022-01613-1 · PubMed 35732831

Last updated 2026-10-22.

Spotted an error or something out of date?Report a problem with this page